Hyperglycemia induces chronic inflammation and oxidative stress in cardiomyocyte, which are the main pathological changes of diabetic cardiomyopathy (DCM).Treatment aimed at these processes may be beneficial in DCM.Phloretin (PHL), a promising natural product, has many pharmacological activities, such as anti-inflammatory, anticancer, and anti-oxid
Control Charts for Processes with an Inherent Between-Sample Variation
A number of processes to which statistical control is applied are subject to various effects that cause random changes in the mean value.The removal of these fluctuations is either technologically impossible or economically disadvantageous under current conditions.The frequent occurrence of signals in the Shewhart chart due to these fluctuations is
Systems Architecture Design Pattern Catalog for Developing Digital Twins
A digital twin is a digital replica of a physical entity to which it is remotely connected.A digital twin can provide a rich representation of the corresponding physical entity and enables sophisticated control for various purposes.Although the concept of the digital twin is largely known, Cable Accessories designing digital twins based systems has
Imputation by feature importance (IBFI): A methodology to envelop machine learning method for imputing missing patterns in time series data.
A new methodology, imputation by feature importance (IBFI), is studied that can be applied to any machine learning method to efficiently fill in any missing or irregularly sampled data.It applies to data missing completely at random (MCAR), missing not at random (MNAR), and missing at random (MAR).IBFI utilizes the feature importance and iterativel