Phloretin Prevents Diabetic Cardiomyopathy by Dissociating Keap1/Nrf2 Complex and Inhibiting Oxidative Stress

Hyperglycemia induces chronic inflammation and oxidative stress in cardiomyocyte, which are the main pathological changes of diabetic cardiomyopathy (DCM).Treatment aimed at these processes may be beneficial in DCM.Phloretin (PHL), a promising natural product, has many pharmacological activities, such as anti-inflammatory, anticancer, and anti-oxid

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Imputation by feature importance (IBFI): A methodology to envelop machine learning method for imputing missing patterns in time series data.

A new methodology, imputation by feature importance (IBFI), is studied that can be applied to any machine learning method to efficiently fill in any missing or irregularly sampled data.It applies to data missing completely at random (MCAR), missing not at random (MNAR), and missing at random (MAR).IBFI utilizes the feature importance and iterativel

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